Research topic
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Detailed summary
Papers investigating the molecular mechanisms underlying Hebbian learning and the involvement of nerve growth factor (NGF) were found and include [1, 2, 4, 5, 8].
Several studies explicitly show the role of NGF in modulating long-term potentiation (LTP) and synaptic plasticity mechanisms directly related to Hebbian learning. For instance, Maguire et al. [1] and Conner et al. [5] demonstrate NGF's enhancement of LTP via TrkA receptor pathways, involving ERK phosphorylation and increased neurotransmitter release. Additionally, Conner et al. [2] provide evidence of NGF’s essential role in hippocampal plasticity and learning, linking it directly to Hebbian mechanisms. Other studies like Kim et al. [4] and Carmignoto et al. [8] explore NGF's LTP-inducing effects and its enhancement of excitatory synaptic transmission, which are crucial for activity-dependent synaptic strengthening in line with Hebbian principles.
Categories of papers
The most important categories to highlight are those that directly investigate the molecular mechanisms underlying Hebbian learning with a strong emphasis on the involvement of hormone-like chemicals such as nerve growth factor (NGF). Additionally, categories that explore related molecular mechanisms of synaptic plasticity and neurotrophic factors, even if not directly addressing Hebbian learning, are also significant.
Precisely Relevant Papers Investigating Molecular Mechanisms of Hebbian Learning Involving NGFDescription: Papers that explicitly investigate the molecular mechanisms underlying Hebbian learning and discuss the involvement of hormone-like chemicals such as nerve growth factor. References: [1, 2, 4, 5, 8]
Related Papers on NGF and Synaptic PlasticityDescription: Studies that explore the role of NGF in synaptic plasticity, which could be directly or indirectly connected to Hebbian learning. References: [3, 6, 7, 10, 11]
Studies on Neurotrophins Including NGF but Not Specifically Hebbian LearningDescription: Papers focusing on the role of neurotrophins including NGF in synaptic plasticity or synaptic modulation, without directly addressing Hebbian learning. References: [12, 14, 18, 20, 24]
General Neurotrophic Factor Research Relevant to Synaptic MechanismsDescription: Papers broadly investigating neurotrophic factors (NGF, BDNF, etc.) and their effects on synaptic mechanisms and plasticity. References: [15, 16, 17, 25, 29]